Highway 60 connects Pampa to Amarillo, about an hour to the west/southwest, and to Perryton, an hour to the north..
Those going northwest towards Borger 30 minutes,Dumas 75 minutes or beyond to Dalhart should take 152.
If you are heading south or east, your best bet is to take 70 south for 30 minutes to where it meets I-40 near Groom. I-40 connects Amarillo in the west with Oklahoma City to the east.
If you plan on heading towards Dallas you should stay on 70 past the I-40 junction and catch 287 at Clarendon.
